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Ruthenium‐Catalyzed Allylic Alkylation Reactions: Carbonate‐Based Catalysts and Intermediates
Author(s) -
Hermatschweiler René,
Fernández Ignacio,
Breher Frank,
Pregosin Paul S.,
Veiros Luis F.,
Calhorda Maria José
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200500967
Subject(s) - ruthenium , chemistry , catalysis , cationic polymerization , regioselectivity , carbonate , allylic rearrangement , alkylation , nitrile , medicinal chemistry , oxidative addition , polymer chemistry , organic chemistry
Branching out : A previously unrecognized ruthenium carbonate intermediate is formed during the reaction of an allylic tert ‐butoxycarbonate with the ruthenium complex [Ru(Cp*)(CH 3 CN) 3 ]PF 6 ( 1 ; see scheme). The isolatable carbonate–allyl complex functions very effectively as an allylic alkylation catalyst. These results provide new insights into the mechanism of this ruthenium‐catalyzed reaction.