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Lewis Base Promoters in the Pauson–Khand Reaction: A Different Scenario
Author(s) -
Perez del Valle Carlos,
Milet Anne,
Gimbert Yves,
Greene Andrew E.
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200500955
Subject(s) - acetylene , olefin fiber , chemistry , lewis acids and bases , ligand (biochemistry) , pauson–khand reaction , promoter , base (topology) , product (mathematics) , combinatorial chemistry , catalysis , organic chemistry , mathematics , mathematical analysis , biochemistry , gene expression , gene , receptor , geometry
Irreversiblity effect : The fundamental role of Lewis base promoters L in the Pauson–Khand reaction was studied by DFT calculations. Contrary to the currently held view, these promoters do not accelerate the departure of a second CO ligand from the acetylene dicobalt complex to create the requisite site for olefin coordination, but stabilize the olefin‐insertion product (see scheme), so that product formation is essentially irreversible.