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Residual Dipolar Couplings—A Valuable NMR Parameter for Small Organic Molecules
Author(s) -
Gschwind Ruth M.
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200500634
Subject(s) - residual dipolar coupling , organic molecules , residual , molecule , dipole , small molecule , polymer , chemical physics , materials science , computational chemistry , chemistry , organic chemistry , computer science , composite material , biochemistry , algorithm
The partial alignment of small organic molecules is now also possible in organic solvents by mechanically constrained polymer gels or modified liquid‐crystalline phases. This paves the way to apply residual dipolar couplings to small molecules and thus to use an additional NMR parameter to determine the structure and configuration of small organic molecules (e.g. spiroindene ( 1 ), see picture).