Regio‐ and Stereoselective Approach to 1,2‐Di‐ and 1,1,2‐Trisilylethenes by Cobalt‐Mediated Reaction of Silyl‐Substituted Dibromomethanes with Silylmethylmagnesium Reagents | Zendy

Ohmiya Hirohisa | Zendy; Yorimitsu Hideki | Zendy; Oshima Koichiro | Zendy

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Regio‐ and Stereoselective Approach to 1,2‐Di‐ and 1,1,2‐Trisilylethenes by Cobalt‐Mediated Reaction of Silyl‐Substituted Dibromomethanes with Silylmethylmagnesium Reagents

Author(s) -

Ohmiya Hirohisa,

Yorimitsu Hideki,

Oshima Koichiro

Publication year - 2005

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200500576

Subject(s) - silylation , reagent , stereoselectivity , regioselectivity , chemistry , cobalt , stoichiometry , catalysis , transformation (genetics) , combinatorial chemistry , medicinal chemistry , stereochemistry , organic chemistry , gene , biochemistry

Functional ethenes : Treatment of dibromo(silyl)methanes 2 a with silylmethyl Grignard reagents 1 and catalytic CoCl 2 affords ( E )‐1,2‐disilylethenes 3 a in excellent yields. Dibromodisilylmethanes 2 b undergo a similar transformation to furnish trisilylethenes 3 b with excellent stereo‐ and regioselectivity in the presence of a stoichiometric amount of a cobaltate reagent.

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