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Modified Linear Dextrins (“Acyclodextrins”) as New Chiral Selectors for the Gas‐Chromatographic Separation of Enantiomers
Author(s) -
Sicoli Giuseppe,
Jiang Zhengjin,
Jicsinsky Laszlo,
Schurig Volker
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200500509
Subject(s) - enantiomer , chemistry , chromatography , gas chromatography , chromatographic separation , organic chemistry , alkyl , chiral derivatizing agent , high performance liquid chromatography , chiral column chromatography
Cyclic or acyclic : Not only modified cyclodextrins but also modified linear dextrins like the silylated (R)and acetylated (R 1 ) maltoheptaose derivatives 1 are suitable selectors for separating racemic N ‐trifluoroacetyl‐ O ‐alkyl esters of α‐amino acids by gas chromatography. In the example shown, racemic N ‐trifluoroacetylserine O ‐ethyl ester is resolved.