Premium
Strategies for Catalytic Asymmetric Electrophilic α Halogenation of Carbonyl Compounds
Author(s) -
Oestreich Martin
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200500478
Subject(s) - enantioselective synthesis , halogenation , electrophile , catalysis , halogen , chemistry , organic synthesis , combinatorial chemistry , halogen bond , organic chemistry , alkyl
Mission possible: Today, catalytic asymmetric variants of nearly all fundamental bond‐forming reactions are known, yet catalyst‐controlled enantioselective construction of carbon–halogen bonds (see scheme; X=F, Cl, Br) was still missing. This gap has now been filled by a cornucopia of conceptually diverse approaches that provide a novel tool for asymmetric organic synthesis.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom