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Cobalt‐Catalyzed syn Hydrophosphination of Alkynes
Author(s) -
Ohmiya Hirohisa,
Yorimitsu Hideki,
Oshima Koichiro
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200500255
Subject(s) - cobalt , catalysis , yield (engineering) , chemistry , selectivity , combinatorial chemistry , medicinal chemistry , organic chemistry , physics , thermodynamics
Treatment of terminal and internal alkynes with diphenylphosphane in the presence of catalytic amounts of a base and cobalt( II ) acetylacetonate affords, with perfect and universal syn selectivity, the ( E )‐alkenyldiphenylphosphane derivatives in good yield (see scheme, acac=acetylacetonate).