Alternate Isotope‐Coded Derivatization Assay: An Isotope Dilution Method Applied to the Quantification of Zearalenone in Maize Flour | Zendy

Sforza Stefano | Zendy; Dall'Asta Chiara | Zendy; Moseriti Alessandra | Zendy; Galaverna Gianni | Zendy; Dossena Arnaldo | Zendy; Marchelli Rosangela | Zendy

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Alternate Isotope‐Coded Derivatization Assay: An Isotope Dilution Method Applied to the Quantification of Zearalenone in Maize Flour

Author(s) -

Sforza Stefano,

Dall'Asta Chiara,

Moseriti Alessandra,

Galaverna Gianni,

Dossena Arnaldo,

Marchelli Rosangela

Publication year - 2005

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200500148

Subject(s) - analyte , isotope dilution , zearalenone , chromatography , derivatization , chemistry , reagent , matrix (chemical analysis) , isotope , calibration curve , calibration , dilution , analytical chemistry (journal) , mass spectrometry , detection limit , mathematics , mycotoxin , organic chemistry , food science , physics , statistics , quantum mechanics , thermodynamics

Low‐cost isotope dilution made easy : An alternate reaction of an analyte in a matrix and in a standard solution with isotope‐labeled or unlabeled derivatizing reagents allows quantification of zearalenone in maize flour without the need for a calibration curve. This is possible by direct calculation of the relative response factor for the analyte/internal standard ratio of the sample (see picture).

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