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Relay Ring‐Closing Metathesis—A Strategy for Achieving Reactivity and Selectivity in Metathesis Chemistry
Author(s) -
Wallace Debra J.
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200462753
Subject(s) - metathesis , ring closing metathesis , salt metathesis reaction , intramolecular force , intermolecular force , chemistry , combinatorial chemistry , selectivity , ring (chemistry) , relay , stereochemistry , organic chemistry , catalysis , molecule , physics , polymerization , power (physics) , quantum mechanics , polymer
How can uncooperative alkenes be rendered more susceptible to metathesis reactions? The realization that what is difficult in an intermolecular sense can become straightforward when transposed to a kinetically favorable intramolecular reaction has led to development of relay ring‐closing metathesis (see scheme). This provides a method for directing initiation and propagation of previously unattainable metathesis sequences.