Tunable Imaging of Cells Labeled with MRI‐PARACEST Agents | Zendy

Aime Silvio | Zendy; Carrera Carla | Zendy; Delli Castelli Daniela | Zendy; Geninatti Crich Simonetta | Zendy; Terreno Enzo | Zendy

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Tunable Imaging of Cells Labeled with MRI‐PARACEST Agents

Author(s) -

Aime Silvio,

Carrera Carla,

Delli Castelli Daniela,

Geninatti Crich Simonetta,

Terreno Enzo

Publication year - 2005

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200462566

Subject(s) - irradiation , nuclear magnetic resonance , paramagnetism , chemistry , contrast (vision) , mri contrast agent , magnetic resonance imaging , nuclear medicine , materials science , medicine , optics , physics , radiology , quantum mechanics , nuclear physics

Cell‐tracking experiments by MRI are possible with a novel class of Tb and Eu paramagnetic imaging agents, with which contrast is generated upon irradiation at a specific frequency (see picture). Middle: A) unlabeled; B) Tb‐labeled; C) Eu‐labeled; D) Tb‐ and Eu‐labeled cells. Left: irradiation at ±180 kHz (Tb‐agent‐specific). Right: irradiation at ±15 kHz (Eu‐agent‐specific).

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