An Exceptionally Selective Lead( II )‐Regulatory Protein from  Ralstonia Metallidurans : Development of a Fluorescent Lead( II ) Probe | Zendy

Chen Peng | Zendy; Greenberg Bill | Zendy; Taghavi Safiyh | Zendy; Romano Christine | Zendy; van der Lelie Daniel | Zendy; He Chuan | Zendy

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An Exceptionally Selective Lead( II )‐Regulatory Protein from Ralstonia Metallidurans : Development of a Fluorescent Lead( II ) Probe

Author(s) -

Chen Peng,

Greenberg Bill,

Taghavi Safiyh,

Romano Christine,

van der Lelie Daniel,

He Chuan

Publication year - 2005

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200462443

Subject(s) - fluorescence , chemistry , ralstonia , green fluorescent protein , metal ions in aqueous solution , combinatorial chemistry , biochemistry , lead (geology) , biophysics , ion , computational biology , nanotechnology , gene , biology , physics , materials science , organic chemistry , quantum mechanics , paleontology

Lighting up lead : A Pb 2+ ‐regulatory protein from Ralstonia metallidurans has been converted into a highly sensitive fluorescent Pb 2+ probe (PbR691, turquoise circles in scheme). This fluorescent system reveals that the protein exhibits a surprisingly high binding selectivity towards Pb 2+ ions over other metal ions.

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