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Wound Closure in the Invasive Green Alga Caulerpa taxifolia by Enzymatic Activation of a Protein Cross‐Linker
Author(s) -
Adolph Sven,
Jung Verena,
Rattke Janine,
Pohnert Georg
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200462276
Subject(s) - chemistry , nucleophile , biopolymer , linker , enzyme , esterase , biochemistry , polymer , organic chemistry , catalysis , computer science , operating system
Rapid polymer formation under physiological conditions is triggered upon wounding of the unicellular macroalga C. taxifolia. This process is initiated by esterase‐mediated deacetylation of caulerpenyne ( 1 ). The resulting 1,4‐dialdehyde oxytoxin 2 ( 2 ) instantaneously reacts with nucleophilic groups from proteins to form a cross‐linked biopolymer.
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