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Total Synthesis of (−)‐Colombiasin A and (−)‐Elisapterosin B
Author(s) -
Harrowven David C.,
Pascoe David D.,
Demurtas Daniela,
Bourne Heather O.
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200462268
Subject(s) - cycloaddition , intramolecular force , total synthesis , chemistry , stereochemistry , organic chemistry , catalysis
Intramolecular cycloaddition reactions are central in the total syntheses of colombiasin A ( 1 ) and elisapterosin B ( 2 ) described, which use (−)‐dihydrocarvone as the starting material. A Moore rearrangement of a vinylcyclobutene is used to initiate the cycloaddition.