Synthesis of 1,8‐Naphthyridine C‐Nucleosides and Their Base‐Pairing Properties in Oligodeoxynucleotides: Thermally Stable Naphthyridine:Imidazopyridopyrimidine Base‐Pairing Motifs | Zendy

Hikishima Sadao | Zendy; Minakawa Noriaki | Zendy; Kuramoto Kazuyuki | Zendy; Fujisawa Yuki | Zendy; Ogawa Maki | Zendy; Matsuda Akira | Zendy

Premium

Synthesis of 1,8‐Naphthyridine C‐Nucleosides and Their Base‐Pairing Properties in Oligodeoxynucleotides: Thermally Stable Naphthyridine:Imidazopyridopyrimidine Base‐Pairing Motifs

Author(s) -

Hikishima Sadao,

Minakawa Noriaki,

Kuramoto Kazuyuki,

Fujisawa Yuki,

Ogawa Maki,

Matsuda Akira

Publication year - 2005

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200461857

Subject(s) - pairing , base (topology) , base pair , chemistry , combinatorial chemistry , computer science , mathematics , physics , dna , biochemistry , quantum mechanics , mathematical analysis , superconductivity

Out with the old, in with the new : Novel 1,8‐naphthyridine C‐nucleosides, Na‐N O and Na‐O N (see formulae), were synthesized through Heck coupling reactions. Oligodeoxynucleotides containing the Na‐N O and Na‐O N nucleosides formed extremely stable duplexes by the base‐pairing motifs Na‐N O :Im‐O N and Na‐O N :Im‐N O .

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research