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A Cartridge System for Organometallic Catalysis: Sequential Catalysis and Separation Using Supercritical Carbon Dioxide to Switch Phases
Author(s) -
Solinas Maurizio,
Jiang Jingyang,
Stelzer Othmar,
Leitner Walter
Publication year - 2005
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200461768
Subject(s) - supercritical carbon dioxide , catalysis , supercritical fluid , phosphine , cartridge , solubility , chemistry , extraction (chemistry) , chemical engineering , combinatorial chemistry , materials science , organic chemistry , metallurgy , engineering
A judicious combination of an organometallic catalyst and workup with supercritical CO 2 resulted in a recyclable system for mediating a variety of transformations. Between reactions the catalyst is “switched off” and recovered as a precipitate from the reaction mixture when scCO 2 is introduced. Simultaneously the product is isolated by extraction with scCO 2 . The key is the unique solubility properties of the Rh catalyst arising from the poly(ethyleneglycol) chains in the phosphine ligands (see scheme).