Premium
Enantioselective Total Synthesis of (+)‐Milnamide A and Evidence of Its Autoxidation to (+)‐Milnamide D
Author(s) -
Liu Chaomin,
Masuno Makoto N.,
MacMillan John B.,
Molinski Tadeusz F.
Publication year - 2004
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200461245
Subject(s) - autoxidation , total synthesis , enantioselective synthesis , sponge , natural product , chemistry , stereochemistry , peptide , organic chemistry , catalysis , biology , biochemistry , botany
Spontaneous oxidation of the marine‐sponge‐derived peptide (+)‐milnamide A ( 1 ) to (+)‐milnamide D ( 2 ), which is also a natural product, was observed during the total synthesis of 1 . The absolute configurations of the structures were determined and are also reported.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom