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A Cyclobutadiene Equivalent in the Catalytic Pauson–Khand Reaction
Author(s) -
Gibson Susan E.,
Mainolfi Nello,
Kalindjian S. Barret,
Wright Paul T.
Publication year - 2004
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200460654
Subject(s) - cyclobutadiene , catalysis , pauson–khand reaction , bicyclic molecule , chemistry , scalability , combinatorial chemistry , isolation (microbiology) , scheme (mathematics) , computational chemistry , computer science , organic chemistry , mathematics , molecule , bioinformatics , biology , database , mathematical analysis
A practical and scalable operation : The reaction shown in the scheme, which uses catalytic amounts of hexacarbonyldicobalt, gives access to versatile bicyclic systems, which until now could only be obtained in low quantities by a photochemical process starting from tropolones. An isolation of the primary Pauson–Khand products is not necessary.