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Development of a Ruthenium‐Catalyzed Asymmetric Epoxidation Procedure with Hydrogen Peroxide as the Oxidant
Author(s) -
Tse Man Kin,
Döbler Christian,
Bhor Santosh,
Klawonn Markus,
Mägerlein Wolfgang,
Hugl Herbert,
Beller Matthias
Publication year - 2004
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200460528
Subject(s) - ruthenium , hydrogen peroxide , catalysis , chemistry , combinatorial chemistry , enantioselective synthesis , organic chemistry
Novel pyboxazines and the known pybox ligands are used in the ruthenium‐catalyzed asymmetric epoxidation of olefins with H 2 O 2 (see scheme). This new catalytic system is successful in the conversion of differently substituted aromatic olefins and gives ee values of up to 84 %.
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