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Ru( II ) Tris(bipyridyl) Complexes with Six Oligonucleotide Arms as Precursors for the Generation of Supramolecular Assemblies
Author(s) -
Stewart Kristen M.,
Rojo Javier,
McLaughlin Larry W.
Publication year - 2004
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200460399
Subject(s) - ruthenium , duplex (building) , oligonucleotide , tris , supramolecular chemistry , dna , chemistry , template , combinatorial chemistry , stereochemistry , crystallography , nanotechnology , biochemistry , materials science , catalysis , crystal structure
The 3D starshaped Ru–bpy–DNA complex pictured comprises a ruthenium( II ) tris(bipyridyl) center with six DNA 20‐mer sequences tethered through linkers at its 4‐ and 4′‐positions. The complexes 1 and 2 hybridize with six complementary 20‐mer strands to form duplex arms. Alternatively, the complementary DNA strands in 1 and 2 hybridize with each other to form larger nanoscale assemblies.