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Genetic Engineering of the Nanoscale Structure in Polyelectrolyte–Lipid Self‐Assembled Systems
Author(s) -
Koltover Ilya,
Sahu Sanjukta,
Davis Nicolynn
Publication year - 2004
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200460164
Subject(s) - polyelectrolyte , nanoscopic scale , pulmonary surfactant , nanotechnology , order (exchange) , self assembly , peptide , charge (physics) , chemical physics , chemistry , materials science , physics , polymer , organic chemistry , biochemistry , finance , economics , quantum mechanics
Peptides sandwiched to order : Genetic engineering can be used to prepare charged polypeptides that self‐assemble with oppositely charged surfactants into highly ordered multilayers (see diagram). Nanoscale order on three separate length scales can be controlled in the polyelectrolyte–surfactant self‐assemblies by changing the peptide length, charge, and surfactant composition.