Premium
Total Synthesis of Lepadins B, D, E, and H; Determination of the Configuration of the Latter Three Alkaloids
Author(s) -
Pu Xiaotao,
Ma Dawei
Publication year - 2004
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200460128
Subject(s) - total synthesis , bicyclic molecule , stereochemistry , chemistry , combinatorics , mathematics
A common bicyclic intermediate was used in an efficient strategy towards lepadins B, D, E, and H shown. These alkaloids are members of a family of natural products with diverse biological activity. The described total syntheses of lepadins D, E, and H enabled the full elucidation of their configuration.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom