Premium
Modular Asymmetric Synthesis of Pochonin C
Author(s) -
Barluenga Sofia,
Lopez Pilar,
Moulin Emilie,
Winssinger Nicolas
Publication year - 2004
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200454108
Subject(s) - modular design , chemistry , stereochemistry , group (periodic table) , combinatorial chemistry , computer science , operating system , organic chemistry
Back to its origins : Pochonin C was synthesized in 11 steps from the four fragments shown in the scheme. This asymmetric synthesis and the conversion of pochonin C into radicicol defines the configuration at the center bearing the chlorine atom as S. Ipc=isopenocampheyl, PG=protecting group.