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Multicomponent Magnetic Nanorods for Biomolecular Separations
Author(s) -
Lee KiBum,
Park Sungho,
Mirkin Chad A.
Publication year - 2004
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200454088
Subject(s) - nanorod , rod , variety (cybernetics) , nanotechnology , block (permutation group theory) , biomolecule , nickel , computer science , scheme (mathematics) , magnetic field , field (mathematics) , chemistry , materials science , physics , artificial intelligence , mathematics , medicine , alternative medicine , geometry , organic chemistry , pathology , mathematical analysis , quantum mechanics , pure mathematics
Gold and nickel are the components of nanorods used to separate biomolecules. The rods can act as a high‐surface‐area scaffolding for biospecific recognition events in a variety of bioseparation schemes. The magnetic Ni block not only provides specificity with respect to His‐tagged proteins but also allows one to conveniently remove rods from a solution by using a magnetic field (see scheme).