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In Situ Formation of a Heterobimetallic Chiral [(Salen)Ti IV ]/[(Salen)V V ] Catalyst for the Asymmetric Addition of TMSCN to Benzaldehyde
Author(s) -
Belokon Yuri N.,
North Michael,
Maleev Victor I.,
Voskoboev Nikolay V.,
Moskalenko Margarita A.,
Peregudov Alexander S.,
Dmitriev Andrey V.,
Ikonnikov Nikolai S.,
Kagan Henri B.
Publication year - 2004
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200454031
Subject(s) - metal salen complexes , ethylenediamine , catalysis , chemistry , benzaldehyde , vanadium , polymer chemistry , medicinal chemistry , trimethylsilyl cyanide , ether , trimethylsilyl , titanium , organic chemistry
A mixed complex which results from two salen‐derived V V and Ti IV complexes ( 1 and 2 ), catalyzes the trimethylsilylcyanation of aldehydes. The reaction kinetics are largely determined by the titanium‐derived portion, whereas the configuration of the mandelonitrile trimethylsilyl ether products is determined by the slower vanadium part of the catalyst. salen= N,N'‐ bis(salicylaldehydo)ethylenediamine.