Premium
Concise Total Synthesis and Structure Assignment of TAN‐1085
Author(s) -
Ohmori Ken,
Mori Keiji,
Ishikawa Yuji,
Tsuruta Hideyuki,
Kuwahara Shunsuke,
Harada Nobuyuki,
Suzuki Keisuke
Publication year - 2004
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200453801
Subject(s) - total synthesis , regioselectivity , tandem , computer science , combinatorial chemistry , stereochemistry , chemistry , organic chemistry , engineering , catalysis , aerospace engineering
Rapid access to the tetracyclic core of TAN‐1085 ( 1 ) was possible by exploiting three efficient processes: a tandem electrocyclic reaction (A), a pinacol cyclization (B), and a regioselective monobenzoylation of a 1,2‐diol (C), which allowed the first total synthesis of 1 .
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom