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Cover Picture: Expanding the Functional Group Compatibility of Small‐Molecule Microarrays: Discovery of Novel Calmodulin Ligands (Angew. Chem. Int. Ed. 21/2003)
Author(s) -
BarnesSeeman David,
Park Seung Bum,
Koehler Angela N.,
Schreiber Stuart L.
Publication year - 2003
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200390464
Subject(s) - calmodulin , cover (algebra) , dna microarray , molecule , small molecule , chemistry , int , computational biology , biophysics , nanotechnology , materials science , biology , biochemistry , computer science , enzyme , engineering , organic chemistry , gene , mechanical engineering , gene expression , operating system
Small‐Molecule Microarrays have provided a robust and scalable means of searching for new small‐molecule–protein interactions. The cover picture shows the protein calmodulin binding to a small molecule that was immobilized on a glass surface by using a novel slide/capture method. More about this method and its use is given by S. L. Schreiber et al. on page 2376ff.