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Cover Picture: Transition‐Metal‐Free Suzuki‐Type Coupling Reactions (Angew. Chem. Int. Ed. 12/2003)
Author(s) -
Leadbeater Nicholas E.,
Marco Maria
Publication year - 2003
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200390339
Subject(s) - suzuki reaction , aryl , palladium , chemistry , coupling (piping) , catalysis , transition metal , halide , coupling reaction , polymer chemistry , combinatorial chemistry , organic chemistry , materials science , composite material , alkyl
Biaryl compounds can be prepared in an aqueous Suzuki‐type coupling reaction without the need for a transition‐metal catalyst. The Suzuki coupling reaction (palladium‐catalyzed coupling of aryl halides with boronic acids) has virtually become the method of choice for the synthesis of biaryl compounds. Under the right conditions, however, it is possible to perform catalyst‐free Suzuki‐type couplings. Further details are reported in the Communication by N. E. Leadbeater and M. Marco on page 1407 ff.