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Optimized NMR Spectroscopic Method for the Configurational Analysis of Chemically Equivalent Vicinal Protons
Author(s) -
Luy Burkhard,
Hauser Gerd,
Kirschning Andreas,
Glaser Steffen J.
Publication year - 2003
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200390335
Subject(s) - homonuclear molecule , vicinal , spins , coupling constant , chemical shift , chemistry , realization (probability) , molecule , sensitivity (control systems) , computational chemistry , spectral line , nuclear magnetic resonance , resonance (particle physics) , j coupling , simple (philosophy) , coupling (piping) , nmr spectra database , molecular physics , nuclear magnetic resonance spectroscopy , physics , stereochemistry , materials science , atomic physics , organic chemistry , quantum mechanics , mathematics , condensed matter physics , statistics , philosophy , electronic engineering , engineering , epistemology , metallurgy
Differentiating the identical : The measurement of homonuclear coupling constants of spins with identical chemical shifts (as observed in 1,2‐disubstituted ethenes) provides important structural information, but its experimental realization is not trivial. A new method results in high sensitivity and simple spectra (see picture) that are easy to interpret. The underlying principle of this method is not limited to symmetric molecules with equivalent spins, but can also be applied to olefinic protons that have similar resonance frequencies.