Total Synthesis of Phorboxazole A

Asymmetric allylation reactions of stannyl‐derived allyldiazaborolanes, a stereoselective cationic cyclization reaction for the formation of the fully substituted C22–C26 tetrahydropyran, and the use of a Julia olefination for the incorporation of the sensitive C37–C46 dienyl system are key features of a highly convergent, stereocontrolled total synthesis of phorboxazole A (see structure).