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Molecular Mousetraps: Gas‐Phase Studies of the Covalent Coupling of Noncovalent Complexes Initiated by Reactive Carbenes Formed by Controlled Activation of Diazo Precursors
Author(s) -
Julian Ryan R.,
May Jeremy A.,
Stoltz Brian M.,
Beauchamp J. L.
Publication year - 2003
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200390258
Subject(s) - diazo , carbene , dissociation (chemistry) , chemistry , covalent bond , reactive intermediate , non covalent interactions , intermolecular force , gas phase , molecule , photochemistry , polymer chemistry , computational chemistry , organic chemistry , catalysis , hydrogen bond
The covalent linking of noncovalently bound host–guest complexes in the gas phase is achieved by the formation of a highly reactive carbene from the host molecule, which is generated by collision‐activated dissociation. Possible mechanisms for the resulting intermolecular reactions are explored by theory and experiment.