Preparation and Asymmetric Hydrogenation of β‐Aryl‐Substituted β‐Acylaminoacrylates | Zendy

You Jingsong | Zendy; Drexler HansJoachim | Zendy; Zhang Songlin | Zendy; Fischer Christine | Zendy; Heller Detlef | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Preparation and Asymmetric Hydrogenation of β‐Aryl‐Substituted β‐Acylaminoacrylates

Author(s) -

You Jingsong,

Drexler HansJoachim,

Zhang Songlin,

Fischer Christine,

Heller Detlef

Publication year - 2003

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200390242

Subject(s) - norbornadiene , aryl , catalysis , ferrocene , chemistry , asymmetric hydrogenation , substrate (aquarium) , function (biology) , enantioselective synthesis , organic chemistry , medicinal chemistry , combinatorial chemistry , alkyl , oceanography , electrode , evolutionary biology , geology , electrochemistry , biology

The Rh‐catalyzed asymmetric hydrogenation of β‐aryl‐substituted ( E )‐β‐acylaminoacrylates, which were isolated for the first time, with, for example [Rh{( R,R )‐(Et‐FerroTANE)}(nbd)] + as catalyst (see picture) proceeds under very mild conditions (25 °C, normal pressure) and high substrate/catalyst ratios with very good enantioselectivity (Et‐FerroTANE=(+)‐1,1′‐bis(2,4‐diethylphosphyltane)ferrocene, nbd=3,5‐norbornadiene).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research