Premium
Application of HRMAS 1 H NMR Spectroscopy To Investigate Interactions between Ligands and Synthetic Receptors
Author(s) -
Händel Heidi,
Gesele Elke,
Gottschall Klaus,
Albert Klaus
Publication year - 2003
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200390133
Subject(s) - chemistry , intramolecular force , nuclear magnetic resonance spectroscopy , solvent , spectroscopy , computational chemistry , stereochemistry , organic chemistry , physics , quantum mechanics
Towards an understanding of chromatographic separation processes : The effect of the solvent composition on the strength of interaction between a chromatographic support and different organic substrates can be monitored by the relative intensity of the intramolecular negative transferred NOE effect (trNOE). The strength of interaction of different synthetic stationary phases with model substrates could be evaluated as changes in the observed trNOE (see picture Y=CH 2 or NH, R 1 =CH 3 , R 2 =phenyl).