Iron‐Containing Nucleoside Analogues with Pronounced Apoptosis‐Inducing Activity | Zendy

Schlawe Daniel | Zendy; Majdalani André | Zendy; Velcicky Juraj | Zendy; Heßler Erik | Zendy; Wieder Thomas | Zendy; Prokop Aram | Zendy; Schmalz HansGünther | Zendy

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Iron‐Containing Nucleoside Analogues with Pronounced Apoptosis‐Inducing Activity

Author(s) -

Schlawe Daniel,

Majdalani André,

Velcicky Juraj,

Heßler Erik,

Wieder Thomas,

Prokop Aram,

Schmalz HansGünther

Publication year - 2004

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200353132

Subject(s) - apoptosis , nucleoside , tumor cells , programmed cell death , chemistry , nucleoside analogue , apoptotic cell death , biochemistry , stereochemistry , cancer research , biology

Bioactive organometallic compounds: Iron‐containing nucleoside analogues, which can be stereoselectively synthesized in a few steps starting from simple carbohydrates, cause tumor cells to undergo apoptosis (programmed cell death; see picture for the typical morphological characteristics of BJAB tumor cells after apoptosis).

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