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A Nucleoside Conjugate Containing a Metallacarborane Group and Its Incorporation into a DNA Oligonucleotide
Author(s) -
Olejniczak Agnieszka B.,
Plešek Jaromir,
Křiž Otomar,
Lesnikowski Zbigniew J.
Publication year - 2003
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200352505
Subject(s) - oligonucleotide , conjugate , nucleoside , chemistry , dna , primer (cosmetics) , combinatorial chemistry , polymerase , microbiology and biotechnology , biochemistry , biology , organic chemistry , mathematical analysis , mathematics
Nucleoside–metallacarborane conjugates (for example, T BEMC ; see picture with low toxicity were synthesized and coupled as a redox label to DNA oligonucleotide. The labeled oligonucleotide acted as a primer for Taq polymerase.