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Catalysis‐Based Total Synthesis of Latrunculin B
Author(s) -
Fürstner Alois,
De Souza Dominic,
ParraRapado Liliana,
Jensen Jon T.
Publication year - 2003
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200352413
Subject(s) - catalysis , molecule , chemistry , combinatorial chemistry , nanotechnology , stereochemistry , biophysics , materials science , biology , biochemistry , organic chemistry
The highly selective actin‐binding latrunculins (e.g. 1 ) play a prominent role as probe molecules in chemical biology. A highly concise, productive, and inherently flexible approach to 1 illustrates the excellent profile and use of metal‐catalyzed CC bond formations.
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