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Gold( III ) Chloride Catalyzed Domino Processes with Isobenzopyrylium Cation Intermediates
Author(s) -
Dyker Gerald,
Hildebrandt Dirk,
Liu Jianhui,
Merz Klaus
Publication year - 2003
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200352160
Subject(s) - domino , benzaldehyde , chemistry , nucleophile , olefin fiber , catalysis , potpourri , chloride , combinatorial chemistry , medicinal chemistry , organic chemistry , botany , biology
A potpourri of remarkable reactions is initiated by the AuCl 3 ‐catalyzed cyclization of an ortho ‐alkynyl benzaldehyde. In the presence of an olefin or an electron‐rich heteroarene as a dienophile or nucleophile, this cyclization provides selective access to a broad variety of polycyclic structures (see scheme).