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Conformative Coupling of Two Conformational Molecular Switches
Author(s) -
Karle Michael,
Bockelmann Dirk,
Schumann Dirk,
Griesinger Christian,
Koert Ulrich
Publication year - 2003
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200352130
Subject(s) - decalin , ring (chemistry) , unit (ring theory) , coupling (piping) , crystallography , molecule , flip flop , chemistry , stereochemistry , materials science , optoelectronics , psychology , organic chemistry , mathematics education , metallurgy , catalysis , cmos
Passing on information . Two conformational switches, decalin units, were coupled to a 14‐membered bislactam ring (see formula, TBDPS= tert ‐butyldiphenylsilyl). Removal of a bisacetal clamp on the left side of the molecule resulted in a double ring‐flip of the left decalin unit. Conformational coupling through the bislactam unit led to a double ring‐flip in the right decalin unit.