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New Reactions of IBX: Oxidation of Nitrogen‐ and Sulfur‐Containing Substrates To Afford Useful Synthetic Intermediates
Author(s) -
Nicolaou K. C.,
Mathison Casey J. N.,
Montag Tamsyn
Publication year - 2003
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200352076
Subject(s) - chemistry , sulfur , toolbox , organic chemistry , nitrogen , combinatorial chemistry , computer science , programming language
New reactions for the synthetic toolbox : 2‐Iodoxybenzoic acid (IBX) was employed to access a diverse array of useful synthetic intermediates. Among other transformations, the developed chemistry converts amines into imines, dithianes into carbonyl groups, N‐heterocycles into N‐heteroaromatic compounds, and hydroxylamines into oximes in high yields.