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Chloride Transport Across Vesicle and Cell Membranes by Steroid‐Based Receptors
Author(s) -
Koulov Atanas V.,
Lambert Timothy N.,
Shukla Rameshwer,
Jain Mahim,
Boon J. Middleton,
Smith Bradley D.,
Li Hongyu,
Sheppard David N.,
Joos JeanBaptiste,
Clare John P.,
Davis Anthony P.
Publication year - 2003
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200351957
Subject(s) - valinomycin , antiporter , vesicle , chemistry , biophysics , membrane , ion transporter , receptor , chloride , efflux , microbiology and biotechnology , biochemistry , biology , organic chemistry
Crossing the barriers : Membrane transport, a well‐established phenomenon for neutral cation receptors such as valinomycin, has been demonstrated for the anion‐binding “cholapods”. The cholapods promote chloride efflux from vesicles by an antiport mechanism and mediate anion flow through live cells grown as epithelia (see schematic representation).