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Carbonylbiscaprolactam: A Versatile Reagent for Organic Synthesis and Isocyanate‐Free Urethane Chemistry
Author(s) -
Maier Steffen,
Loontjens Ton,
Scholtens Boudewijn,
Mülhaupt Rolf
Publication year - 2003
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200351867
Subject(s) - chemistry , reagent , nucleophile , isocyanate , ring (chemistry) , selectivity , catalysis , organic chemistry , organic synthesis , combinatorial chemistry , polyurethane
The power of the rings : The reactions of carbonylbiscaprolactam (CBC, 1 ) with amines and alcohols proceed either by ring elimination (RE) or by ring opening (RO). The conversion and selectivity of these reactions were optimized in studies with various hydroxy and amino compounds, catalysts, reaction temperatures, and ratios of 1 /nucleophile.