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High‐Throughput Synthesis of Phosphonate‐Based Inorganic–Organic Hybrid Compounds under Hydrothermal Conditions
Author(s) -
Stock Norbert,
Bein Thomas
Publication year - 2004
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200351718
Subject(s) - phosphonate , hydrothermal circulation , hydrothermal synthesis , throughput , combinatorial synthesis , phase (matter) , phase diagram , combinatorial chemistry , nanotechnology , materials science , solid phase synthesis , zinc , organic synthesis , chemistry , computer science , chemical engineering , organic chemistry , engineering , catalysis , peptide , telecommunications , biochemistry , wireless
A new phase in combinatorial chemistry : High‐throughput methods for hydrothermal reactions including automated solid‐dosing and pH‐measurement capabilities have been applied to the synthesis of five novel zinc phosphonocarboxylates and seven novel metal tetraphosphonates. This automated combinatorial synthesis and characterization method allows a large parameter space to be explored rapidly (see phase diagram) and has great potential for materials science.

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