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Intramolecular Aromatic Amination through Iron‐Mediated Nitrene Transfer
Author(s) -
Jensen Michael P.,
Mehn Mark P.,
Que Lawrence
Publication year - 2003
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200351605
Subject(s) - nitrene , chemistry , intramolecular force , amination , moiety , substituent , ring (chemistry) , amine gas treating , medicinal chemistry , stereochemistry , organic chemistry , catalysis
An iron( III ) anilide complex can be formed through the reaction of phenyl‐ N ‐tosylimidoiodinane with the non‐heme iron complex [(6‐PhTPA)Fe II (NCCH 3 ) 2 ](ClO 4 ) 2 (TPA= tris(2‐pyridylmethyl)amine), in which an efficient transfer of the nitrene moiety to the ortho position of the α‐phenyl substituent is achieved (a hypothetical structure of the complex is illustrated, in which the tolyl ring, except for the ipso carbon atom, is excluded for clarity; Fe pink, S yellow, O red, N blue).