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Functionalized 1,2‐Dihydronaphthalenes from the Cu(OTf) 2 ‐Catalyzed [4+2] Cycloaddition of o ‐Alkynyl(oxo)benzenes with Alkenes
Author(s) -
Asao Naoki,
Kasahara Taisuke,
Yamamoto Yoshinori
Publication year - 2003
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200351390
Subject(s) - cycloaddition , catalysis , chemistry , medicinal chemistry , organic chemistry
The [4+2] cycloaddition reaction between o ‐alkynyl(oxo)benzene 1 and olefins 2 in the presence of a catalytic amount of Cu(OTf) 2 afforded 1,2‐dihydronaphthalene derivatives 3 bearing an oxo function at the 1‐position. The reaction proceeds most probably through the formation of benzo[ c ]pyrylium cupric ate complex.