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Highly Efficient Peptide Bond Formation to Functionalized Wells‐Dawson‐Type Polyoxotungstates
Author(s) -
Bareyt Sébastian,
Piligkos Stergios,
Hasenknopf Bernold,
Gouzerh Pierre,
Lacôte Emmanuel,
Thorimbert Serge,
Malacria Max
Publication year - 2003
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200351346
Subject(s) - chemistry , peptide , amino acid , combinatorial chemistry , computer science , stereochemistry , biochemistry
Making derivatives of organic side chains on polyoxometalates is an important prerequisite for their application in biology. Compounds α 1 ‐ and α 2 ‐[P 2 W 17 O 61 {Sn(CH 2 ) 2 CO 2 H}] 7− (depicted) were prepared for the first time and coupled with alcohols and amines, including C‐protected amino acids.