Di(isopropylprenyl)borane: A New Hydroboration Reagent for the Synthesis of Alkyl and Alkenyl Boronic Acids | Zendy

Kalinin Alexey V. | Zendy; Scherer Stefan | Zendy; Snieckus Victor | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Di(isopropylprenyl)borane: A New Hydroboration Reagent for the Synthesis of Alkyl and Alkenyl Boronic Acids

Author(s) -

Kalinin Alexey V.,

Scherer Stefan,

Snieckus Victor

Publication year - 2003

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200351312

Subject(s) - hydroboration , chemistry , boranes , borane , reagent , organic chemistry , alkyl , reactivity (psychology) , hydrolysis , selectivity , combinatorial chemistry , boron , catalysis , medicine , alternative medicine , pathology

The best of the old : The new hydroboration reagent 1 combines the selectivity of disiamylborane ( 2 ) with the reactivity towards carbonyls of allyl boranes 3 . Conventional oxidative workup conditions are avoided, as facile hydrolysis in protic media provides the corresponding boronic acids with up to 99 % anti‐Markovnikov selectivities. A one‐pot hydroboration/Suzuki–Miyaura protocol adds to the synthetic value of 1 .

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research