Premium
InBr 3 ‐Catalyzed Cyclization of Glycals with Aryl Amines
Author(s) -
Yadav Jhillu S.,
Reddy Basi V. S.,
Rao Katta V.,
Saritha Raj Kavuda,
Prasad Atlaluri R.,
Kiran Kumar Singarapu,
Kunwar Ajit C.,
Jayaprakash Panjula,
Jagannath Bulusu
Publication year - 2003
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200351267
Subject(s) - tribromide , aryl , catalysis , chemistry , organic chemistry , combinatorial chemistry , medicinal chemistry , stereochemistry , alkyl
A new class of carbohydrate analogues , benzo‐fused heterobicycles 1 , can be prepared by cyclization of D ‐glucals with aryl amines in the presence of 10 mol % indium tribromide under mild and convenient reaction conditions [Eq. (1)]. The structure and configuration of the products were established by extensive NMR experiments and molecular modeling studies.