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Amine‐Catalyzed Epoxidation of Alkenes: A New Mechanism for the Activation of Oxone
Author(s) -
Armstrong Alan
Publication year - 2004
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200301716
Subject(s) - catalysis , chemistry , mechanism (biology) , amine gas treating , organocatalysis , reaction mechanism , organic chemistry , combinatorial chemistry , enantioselective synthesis , philosophy , epistemology
Some of the most promising systems emerging for the catalytic asymmetric epoxidation of alkenes involve the activation of oxone (active constituent KHSO 5 ). The discovery of catalysis by amines is an exciting development in this area of organocatalysis, and a new mechanism for the activation of oxone has been advanced with important consequences (see scheme).