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Layer‐by‐Layer Deposition of Polyelectrolytes—A Versatile Tool for the In Vivo Repair of Blood Vessels
Author(s) -
Groth Thomas,
Lendlein Andreas
Publication year - 2004
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200301708
Subject(s) - polyelectrolyte , layer by layer , layer (electronics) , deposition (geology) , polymerization , materials science , adsorption , nanotechnology , in vivo , chemistry , biomedical engineering , polymer , biology , composite material , organic chemistry , engineering , paleontology , microbiology and biotechnology , sediment
Layer‐by‐layer adsorption of polygenic polyelectrolytes is a promising method of treatment in which multilayers are formed on the inner arterial wall (see scheme). An advantage of this technique, which has already proved successful in animal models, is that it is very simple to apply, in contrast to in situ polymerization, which requires irradiation with UV light. Furthermore, it is rapid and allows the incorporation of active drugs in the layer.