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Preparation of Resolved Fourfold Symmetric Amphiphilic Helices Using Chiral Metallacrown Building Blocks
Author(s) -
CutlandVan Noord Annabel D.,
Kampf Jeff W.,
Pecoraro Vincent L.
Publication year - 2002
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200290010
Subject(s) - amphiphile , helix (gastropod) , chirality (physics) , chemistry , hydroxamic acid , ligand (biochemistry) , stereochemistry , crystallography , phenylalanine , copolymer , amino acid , receptor , organic chemistry , physics , biochemistry , biology , ecology , chiral symmetry breaking , quantum mechanics , snail , nambu–jona lasinio model , quark , polymer
The chirality of the ligand determines the nature of the helix : Coordination of a chain of [15]metallacrown‐5 complexes based on phenylalanine hydroxamic acid results in an amphiphilic metallohelix with a 4 1 screw axis. The use of the L isomer of the acid gives the right‐handed helix (see left structure) while the D isomer gives the mirror image structure.
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