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Phototriggered Drug Release from Functionalized Oligonucleotides by a Molecular Beacon Strategy
Author(s) -
Okamoto Akimitsu,
Tanabe Kazuhito,
Inasaki Takeshi,
Saito Isao
Publication year - 2003
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200250832
Subject(s) - molecular beacon , oligonucleotide , intramolecular force , quenching (fluorescence) , chemistry , combinatorial chemistry , drug , molecule , photochemistry , nanotechnology , fluorescence , materials science , stereochemistry , organic chemistry , physics , biochemistry , pharmacology , gene , biology , quantum mechanics
More than just a light switch : A phototriggered molecule‐releasing system controlled through intramolecular triplet quenching by using a molecular beacon strategy with photoactive probe oligodeoxynucleotides (ODNs) has been developed (see picture).